Endometrial biopsy with histological examination

Endometrial biopsy is a medical procedure in which a small sample of tissue is taken from the lining of the uterus (endometrium). The sample is sent to a laboratory for histological examination to assess the condition of the endometrium, diagnose pathological changes, and detect various gynecological conditions. The service price does not include the cost of histological examination.

The endometrium is the inner lining of the uterus that renews itself each month during the menstrual cycle and prepares for the implantation of a fertilized egg. An endometrial biopsy is a procedure in which a thin instrument (such as a Pipelle catheter or curette) is inserted through the cervix into the uterine cavity to obtain a small sample of endometrial tissue. The sample is then sent to a pathology laboratory for histological analysis.

When Is an Endometrial Biopsy Needed?

An endometrial biopsy may be recommended in the following situations:

• Abnormal uterine bleeding: irregular bleeding, heavy menstrual bleeding, or postmenopausal bleeding.
• Endometrial thickening (hyperplasia): detected during an ultrasound examination.
• Suspected endometrial polyps or tumors: when further diagnostic clarification is required.
• Infertility or recurrent miscarriages: when endometrial pathology is suspected as a contributing factor.
• Hormonal imbalance: when assessment of the endometrial response to hormone therapy is needed.
• Before assisted reproductive procedures: to evaluate the readiness of the endometrium for embryo implantation.

Procedure at the Clinic:

An endometrial biopsy is performed in a gynecology office.

1. Consultation: the gynecologist evaluates the patient's condition, symptoms, and medical history.
2. Preparation: the patient is positioned in a gynecological examination chair. The cervix is disinfected, and local anesthesia may be administered if necessary.
3. Tissue sampling: the physician gently inserts the instrument through the cervix into the uterine cavity and collects a small sample of endometrial tissue. The procedure may cause mild discomfort or cramping.
4. Laboratory analysis: the collected sample is sent to a pathology laboratory for histological examination.

Interpretation of Results:

The histological examination provides valuable information about the condition of the endometrium and can help diagnose inflammatory processes, hyperplasia, polyps, precancerous changes, or tumors. These findings are important for the treating physician, enabling an accurate diagnosis and the development of an appropriate treatment plans.